Pleural effusion developed in 6 of 31 patients undergoing esophageal v
ariceal sclerotherapy using absolute alcohol. The effusions were small
, appeared within 48 hours of sclerotherapy, and disappeared without t
reatment within 7 days in all six patients. Prevalence of chest pain w
as significantly greater when pleural effusions developed than when pl
eural effusions did not develop (83% of patients versus 19%, respectiv
ely, p < 0.05). The persistence of chest pain was also significantly g
reater when pleural effusions developed than when they did not develop
(80% of patients versus 19%, respectively, p < 0.05). We conclude tha
t pleural effusion occurs frequently after esophageal variceal sclerot
herapy with alcohol and is commonly associated with chest pain.