Six patients with severe hemorrhagic cystitis unresponsive to traditio
nal localized therapy were treated with percutaneous nephrostomy for d
iversion of urine. Bladder hemorrhage ceased in 3 patients, decreased
in 2 and was unchanged in 1. In 1 patient with profound thrombocytopen
ia perirenal hematoma developed as a result of the nephrostomy placeme
nt but th's complication was self-limited and did not require surgery.
Our experience with these 6 patients indicates that nephrostomy diver
sion is safe and effective in most cases of hemorrhagic cystitis refra
ctory to traditional, nonoperative therapy. Percutaneous urine diversi
on may obviate the need for surgical urinary diversion in patients who
have intractable hemorrhagic cystitis.