Noncardiac chest pain is a common costly phenomenon in the cardiology
setting. Recent research suggests that panic disorder, a highly distre
ssful yet treatable anxiety disorder, occurs in a significant proporti
on of noncardiac chest pain patients. This article reviews research on
the prevalence of panic disorder in patients seen in cardiology setti
ngs for unexplained chest pain. Financial, psychosocial, and historica
l aspects of noncardiac chest pain are described. Panic disorder and t
he potential consequences of its nonrecognition by physicians are exam
ined. Current psychological and pharmacologic treatments are reviewed.
Recommendations on the management of panic patients in the cardiology
setting are provided.