BIOLOGICAL SIGNIFICANCE OF X-CHROMOSOME INACTIVATION PATTERN IN SUBFERTILE COWS CARRYING AN X-AUTOSOME TRANSLOCATION

Authors
BEREPUBO NA PINHEIRO LE BASRUR PK
Citation
Na. Berepubo et al., BIOLOGICAL SIGNIFICANCE OF X-CHROMOSOME INACTIVATION PATTERN IN SUBFERTILE COWS CARRYING AN X-AUTOSOME TRANSLOCATION, Discovery and innovation, 5(1), 1993, pp. 57-62
Citations number
NO
Categorie Soggetti
Multidisciplinary Sciences
Journal title
Discovery and innovation → ACNP
ISSN journal
1015079X
Volume
5
Issue
1
Year of publication
1993
Pages
57 - 62
Database
ISI
SICI code
1015-079X(1993)5:1<57:BSOXIP>2.0.ZU;2-O
Abstract
The genetically inactivated X-chromosome in subfertile cows carrying a n X-autosome translocation was determined. Identification was by compa rative measurement of the sizes of the Barr body and the drumstick, in the translocation carriers as well as in the control (normal) of cows , and by autoradiography. The normal X-chromosome of the translocation carriers was found to be subject to preferential genetic inactivation . The biological significance of this observation is discussed in rela tion to previous cases of X-autosome translocation in man and the mous e.