N. Arneborg et al., THE EFFECT OF GROWTH-RATE AND OTHER GROWTH-CONDITIONS ON THE LIPID-COMPOSITION OF ESCHERICHIA-COLI, Applied microbiology and biotechnology, 39(3), 1993, pp. 353-357
Escherichia coli was grown as a continuous culture at various defined
conditions of temperature, pH, aeration rate and dilution rate. The li
pids were extracted from disrupted cells and the relative fatty acid c
ontent of the individual and total phospholipids was determined. The l
ipid composition of E. coli was shown to change with the fermentation
conditions. Interestingly, E. coli adapted to high growth rates and to
low oxygen tension by changing the lipid composition of the membrane
in exactly the same way, thus indicating a common effect.