Postoperative: nausea and vomiting are still common problems after gen
eral anesthesia, especially in ambulatory surgery. Drug therapy is oft
en complicated with central nervous system symptoms. We studied a nonp
harmacological method of therapy-acupressure-at the Pericardium 6 (P.6
) (Nei-Guan) meridian point. Two hundred consecutive healthy patients
undergoing a:variety of short surgical procedures were included in a r
andomized, double-blind study: 108 patients were in the acupressure gr
oup (Group 1) and 92 patients were in the control group (Group 2). Sph
erical beads of acupressure bands were placed at the P.6 points in the
anterior surface of both forearms in Group 1 patients, while in Group
2 they were placed inappropriately on the posterior surface. The acup
ressure bands were placed before induction of anesthesia and were remo
ved 6 h postoperatively. They were covered with a soft cotton wrapping
to conceal them from the blinded observer who evaluated the patients
for presence of nausea and vomiting and checked the order sheet for an
y antiemetics prescribed. In both groups, the age, gender, height, wei
ght, and type and duration of surgical procedures were all comparable
without significant statistical difference. In Group 1, only 25 of 108
patients (23%) had nausea and vomiting as compared to Group 2, in whi
ch 38 of 92 patients (41%) had nausea and vomiting (P = 0.0058). We co
ncluded that acupressure at the P.6 (Nei-Guan) point is an effective p
rophylaxis for postsurgical nausea and vomiting and therefore a good a
lternative to conventional antiemetic treatment.