J. Payer et al., CIRCADIAN RHYTHMICITY AND CROSS-CORRELATION OF PLASMA GASTRIN, CORTISOL AND SOMATOSTATIN LEVELS IN ULCERATIVE-COLITIS PATIENTS AND HEALTHY-SUBJECTS, Hepato-gastroenterology, 40(3), 1993, pp. 272-275
Gastrin, somatostatin and cortisol circadian (24 hours) rhythmicity wa
s confirmed in healthy subjects. Gastrin and cortisol circadian rhythm
icity was studied and also established in patients with ulcerative col
itis (UC). UC patients were found to have a lower 24-hour amplitude of
plasma cortisol and a shorter acrophase of plasma gastrin. Gastrin co
rrelated positively with somatostatin and negatively with cortisol.