Background: Bone marrow transplantation for the treatment of malignanc
ies is on the increase. Unfortunately, there are no well-validated inf
ection control guidelines for this highly susceptible population. Meth
ods: Literature was reviewed concerning infection risks and interventi
ons to decrease risks for bone marrow transplant recipients. Results:
Definitive information was generally lacking. However, basic ''common
sense'' infection control recommendations for bone marrow transplantat
ion were made in the following areas: air ventilation systems, design
issues, environmental services, patient care issues, barrier precautio
ns, nosocomial surveillance, and discharge planning. Recommendations m
ust be tailored to each facility or setting. Conclusion: We conclude t
hat validation of many of these recommendations is necessary to provid
e optimum care for bone marrow transplant recipients.