WATER-SOLUBLE POLYMERS HAVING LOWER CRITI CAL SOLUTION TEMPERATURE FOR TARGETED DELIVERY OF DRUGS AND OTHER COMPOUNDS

Authors
VALUEV LI ZEFIROVA ON OBYDENNOVA IV PLATE NA
Citation
Li. Valuev et al., WATER-SOLUBLE POLYMERS HAVING LOWER CRITI CAL SOLUTION TEMPERATURE FOR TARGETED DELIVERY OF DRUGS AND OTHER COMPOUNDS, Vysokomolekularnye soedinenia. Seria A, 35(1), 1993, pp. 10000083-10000086
Citations number
12
Categorie Soggetti
Polymer Sciences
Journal title
Vysokomolekularnye soedinenia. Seria A → ACNP
ISSN journal
05075475
Volume
35
Issue
1
Year of publication
1993
Pages
10000083 - 10000086
Database
ISI
SICI code
0507-5475(1993)35:1<10000083:WPHLCC>2.0.ZU;2-H
Abstract
A new approach to the targeted thermally activated transport of chemic al agents and physiologically active compounds is reported. The approa ch involves the immobilization of these compounds on water-soluble pol ymers having a lower solution temperature and heating the delivery sit e above the critical temperature. The approach was verified with tryps in immobilized on opropylacrylamide-acrylamide-N-acryloylphthalimide t ernary copolymers.