Pv. Kulkarni et al., NEW APPROACHES IN MEDICAL IMAGING USING PLASTIC SCINTILLATING DETECTORS, Nuclear instruments & methods in physics research. Section B, Beam interactions with materials and atoms, 79(1-4), 1993, pp. 921-925
A small animal imaging camera was built in our laboratory, using fast
plastic scintillating detectors (tau = 2-4 ns) and position sensitive
photomultipliers (Hamamatsu) digitized using flash ADCs. Pinhole colli
mators were used for I-125 imaging to achieve submillimeter resolution
with scintillating plates of 28 mm radius and 1.5 mm thickness. A hig
h resolution PET module was constructed with arrays of 1.0 mm diameter
plastic scintillating fibers. The feasibility of high resolution imag
ing was demonstrated by the study of brain blood flow in a rat using I
-125 IMP in single photon detection mode and with Cu-64 PTSM by using
PET mode. Construction of single photon and positron emission tomograp
hic imaging systems for small animals and subsequently for human imagi
ng is in progress.