The charts and cranial ultrasounds of 29 infants treated with extracor
poreal membrane oxygenation (ECMO) for respiratory insufficiency secon
dary to meconium aspiration syndrome, primary pulmonary hypertension,
congenital diaphragmatic hernia and/or sepsis were examined to identif
y ultrasound abnormalities. Seventeen (58.6%) developed extra-axial fl
uid collections, only two of which were progressive. Ten (34.5%) devel
oped evidence of intracranial hemorrhage (ICH): seven caudate, one eac
h in the thalamus, parietal and occipital lobes. Eight (27.65%) of the
neonates had seizures while on ECMO, 5 of whom had concurrent ICH.