FLOW-INJECTION CHEMILUMINOMETRIC DETERMINATION OF EPINEPHRINE, NOREPINEPHRINE, DOPAMINE AND L-DOPA

A method is proposed for the determination of 0.0500-1.00 mug ml-1 of epinephrine and L-dopa and 0.100-1.00 mug ml-1 of norepinephrine and d opamine by their chemiluminogenic oxidation with potassium permanganat e in acidic medium, in the presence of formaldehyde, which greatly imp roves the sensitivity. Flow injection allows the measurement of 80 sol utions per hour. The method was also optimized for a continuous-flow s ystem. Comparative results from numerous organic compounds proved the necessity for electron-donating groups on the benzene ring for sensiti ve chemiluminescent characteristics.