AUTOMATIC-DETERMINATION OF AMYLOCAINE AND BROMHEXINE BY ATOMIC-ABSORPTION SPECTROMETRY

An automatic method for the determination of amylocaine and bromhexine hydrochloride by atomic absorption spectrometry (AAS) is proposed. Th e drugs were determined indirectly by formation of reineckates, extrac tion into 1,2-dichloroethane and measurement of chromium in the organi c phase. The chemical conditions and experimental variables influencin g the performance of the flow system of the liquid-liquid extractor we re established. The proposed method allows the determination of amyloc aine and bromhexine at concentrations between 3 and 120 mug ml-1 with a relative standard deviation of 1 and 3%, respectively, even in the p resence of other synthetic drugs.