AN AUTOMATED AEROSOL ACTUATOR - APPLICATION TO THE UNIFORMITY TESTINGOF PHARMACEUTICAL AEROSOL DOSAGE FORMS

Authors
MAZZO DJ ENGERER R EGOVILLE J
Citation
Dj. Mazzo et al., AN AUTOMATED AEROSOL ACTUATOR - APPLICATION TO THE UNIFORMITY TESTINGOF PHARMACEUTICAL AEROSOL DOSAGE FORMS, Journal of pharmaceutical and biomedical analysis, 11(4-5), 1993, pp. 313-321
Citations number
7
Categorie Soggetti
Pharmacology & Pharmacy
Journal title
Journal of pharmaceutical and biomedical analysis → ACNP
ISSN journal
07317085
Volume
11
Issue
4-5
Year of publication
1993
Pages
313 - 321
Database
ISI
SICI code
0731-7085(1993)11:4-5<313:AAAA-A>2.0.ZU;2-#
Abstract
An automated system for valve performance testing to determine net wei ght loss per actuation of pharmaceutical aerosol dosage forms has been developed and is described. The principal element of the system is a novel automatic aerosol actuation device. Details of the validation, c omparison to manual methods of analysis and advantages are presented. The automated system has been shown to be a cost-effective, productive and facile alternative to manual testing.