ANTIMUTAGENIC ACTION OF SUPEROXIDE-DISMUT ASE ON SODIUM AZIDE-INDUCEDMUTAGENESIS IN SALMONELLA-TYPHIMURIUM TA1535

Authors
VOROBYEVA LI CHERDINCEVA TA AVERYANOV AA ABILEV SK
Citation
Li. Vorobyeva et al., ANTIMUTAGENIC ACTION OF SUPEROXIDE-DISMUT ASE ON SODIUM AZIDE-INDUCEDMUTAGENESIS IN SALMONELLA-TYPHIMURIUM TA1535, Genetika, 29(5), 1993, pp. 760-767
Citations number
24
Categorie Soggetti
Genetics & Heredity
Journal title
Genetika → ACNP
ISSN journal
00166758
Volume
29
Issue
5
Year of publication
1993
Pages
760 - 767
Database
ISI
SICI code
0016-6758(1993)29:5<760:AAOSAO>2.0.ZU;2-A
Abstract
It was shown that superoxide dismutase (SOD) decreased the mutagenic a ction of sodium azide (NaN3) and N-methyl-N'-nitro-N-nitrosoguanidine in Salmonella typhimurium TA1535. Catalase and quenchers of hydroxyl r adicals showed, unlike SOD no effect on the mutagenicity of NaN3. Cell extract from propionic acid bacteria also possessed the antimutagenic activity, only partially depending on the SOD activity.