THE INFLUENCE OF MICE IMMUNIZATION WITH H UMAN UMBILICAL-CORD EXTRACTON MICRONUCKEI INDUCTION BY CYCLOPHOSPHAMIDE

Authors
MKRTCHIAN LN NERSESSIAN AK
Citation
Ln. Mkrtchian et Ak. Nersessian, THE INFLUENCE OF MICE IMMUNIZATION WITH H UMAN UMBILICAL-CORD EXTRACTON MICRONUCKEI INDUCTION BY CYCLOPHOSPHAMIDE, Genetika, 29(5), 1993, pp. 866-868
Citations number
8
Categorie Soggetti
Genetics & Heredity
Journal title
Genetika → ACNP
ISSN journal
00166758
Volume
29
Issue
5
Year of publication
1993
Pages
866 - 868
Database
ISI
SICI code
0016-6758(1993)29:5<866:TIOMIW>2.0.ZU;2-K
Abstract
The influence of human umbilical cord extract (HUGE) on mutagenesis in duces by cyclophosphamide in mice bone marrow cells was studied. It wa s shown that HUGE had no clastogenic property and decreased significan tly the number of micronuclei in bone marrow cells of mice during 5 da ys after the last HUGE infection. We suppose that the antimutagenic ef fect is connected with interferon induction by HUGE.