ITSELF AND INTERREGULATION OF CATECHOLAMI NERGIC SYSTEM ACTIVITY

The release of catecholamines in the slices of rat crown cortex was st udied by HPLS. Haloperidol dose-dependently increased the K+-provoked release of endogenous DA, NA and A. The sensitivity of DA receptors wh ich modulated the release of NA was 35.7 times higher than of those mo dulating the release of DA. The sensitivity of DA receptors which modu lated the release of A was 20,000 times higher than of those which mod ulated the release of DA. At this sensitivity of DA receptors, DA was calculated to be effective at a distance of about 10 mm and even more.