Ja. Hall et al., MAMMOGRAPHIC ABNORMALITIES AND THE DETECTION OF CARCINOMA OF THE BREAST, American journal of obstetrics and gynecology, 168(6), 1993, pp. 1677-1682
OBJECTIVE: In an attempt to reduce the number of unnecessary breast bi
opsies, the yield rate of cancer relative to specific types of mammogr
aphically detected abnormality was investigated. STUDY DESIGN: Between
1989 and 1991, 169 patients with an abnormality as detected by mammog
ram but with no palpable mass were reviewed. Abnormalities detected by
mammogram were divided into four types. The rate of biopsy-confirmed
cancer per type of abnormality was calculated. RESULTS: The incidence
of cancer per type of mammographically detected abnormality was as fol
lows: mass 11%, mass with abnormal calcification 21%, abnormal calcifi
cation 22%, and asymmetric density 2%. CONCLUSION: Biopsy is recommend
ed for mammographically detected abnormalities of a mass, a mass with
abnormal calcification, and abnormal calcification without mass. Consi
deration should be given to deferring biopsy in favor of a follow-up s
tudy for asymmetric densities.