THE CONFORMATION OF CYCLO-[(R)-CYSTEINYL-(R)-CYSTEINE] IN SOLUTION

Authors
HORNE A NORTH M PARKINSON JA SADLER IH
Citation
A. Horne et al., THE CONFORMATION OF CYCLO-[(R)-CYSTEINYL-(R)-CYSTEINE] IN SOLUTION, Tetrahedron, 49(26), 1993, pp. 5891-5904
Citations number
16
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
49
Issue
26
Year of publication
1993
Pages
5891 - 5904
Database
ISI
SICI code
0040-4020(1993)49:26<5891:TCOCIS>2.0.ZU;2-9
Abstract
The conformation in solution of the conformationally constrained cycli c dipeptide N-BOC-[cyclo-(R)-cysteinyl-(R)-cysteine] t-butyl ester is investigated by NMR and molecular mechanics techniques. The compound i s found to exist as two slowly interconverting conformations in chloro form, both of which have a cis amide bond.