SYNTHESIS OF BRIDGED BETA-AMINO-ACIDS AND THEIR THERMOLYSIS TO DEHYDRO BETA-AMINO-ACID AND OXAURACIL

Authors
AKSSIRA M DAHDOUH A KASMI H
Citation
M. Akssira et al., SYNTHESIS OF BRIDGED BETA-AMINO-ACIDS AND THEIR THERMOLYSIS TO DEHYDRO BETA-AMINO-ACID AND OXAURACIL, Bulletin des Societes chimiques belges, 102(4), 1993, pp. 227-232
Citations number
19
Categorie Soggetti
Chemistry
Journal title
Bulletin des Societes chimiques belges → ACNP
ISSN journal
00379646
Volume
102
Issue
4
Year of publication
1993
Pages
227 - 232
Database
ISI
SICI code
0037-9646(1993)102:4<227:SOBBAT>2.0.ZU;2-U
Abstract
Reactions of bridged dicarboxylic anhydride derivatives with sodium az ide in THF give the corresponding, N-tert-butyloxycarbonyl beta-aminoe sters 2-(a-c), which can be cyclized to oxanorborno- and norbornouraci ls 6(a-c). Pyrolysis of these adducts leads to dehydro-beta-alanine 5 and oxauracil 7.