CIRCADIAN VARIATIONS OF SUPEROXIDE-DISMUTASE ACTIVITY IN THE RAT PINEAL-GLAND

Authors
CIPOLLANETO J ABDALLA DSP MARKUS RP CAMPA A
Citation
J. Cipollaneto et al., CIRCADIAN VARIATIONS OF SUPEROXIDE-DISMUTASE ACTIVITY IN THE RAT PINEAL-GLAND, Journal of neural transmission, 92(2-3), 1993, pp. 117-123
Citations number
32
Categorie Soggetti
Neurosciences
Journal title
Journal of neural transmission → ACNP
ISSN journal
03009564
Volume
92
Issue
2-3
Year of publication
1993
Pages
117 - 123
Database
ISI
SICI code
0300-9564(1993)92:2-3<117:CVOSAI>2.0.ZU;2-7
Abstract
The 24 h profile of the activity of the antioxidant enzyme superoxide dismutase (SOD) in the pineal gland of rats was studied. Rhythmic anal ysis showed a significant 24 h rhythm with an amplitude of oscillation of 25% of the 24 h mean value, that was 100.34 +/- 1.6 U SOD (nitrite ). An ultradian rhythm of 9 h was also detected. The diurnal profile o f superoxide dismutase activity is discussed in relation to the oxidat ive metabolism of the pineal gland.