CHRONIC NEUROPSYCHOLOGICAL IMPAIRMENT RESULTING FROM DISULFIRAM OVERDOSE

The present case study examines the sequelae of disulfiram overdose an d resulting chronic organic brain syndrome, with a 45-year-old, white, male alcoholic. Previous reports have discussed acute organic brain s yndromes that are reversed after discontinuance of the drug. This part icular case, however, resulted in significant cerebral impairment that was irreversible. Full neuropsychological testing which describes the extent of these neurologic deficits is presented, along with some pos sible reasons for these chronic sequelae.