Sixty-four patients with a histological diagnosis of minimal change ne
phropathy have been followed for a median of 110 months. Patients tran
sferred from paediatric units (11%) had a worse prognosis in that all
became frequent relapsers. Patients who relapsed within three months o
r who went on to become frequent relapsers had a higher 24 hour urine
protein excretion at presentation than patients who did not relapse. A
fter fifteen months of remission relapse was rare; 97% of those who re
lapsed did so within 36 months. Patients who have been off steroids an
d proteinuria free for 36 months might therefore be considered cured.