Despite the marked decline infrequency of neurosyphilis over the past
three decades in the United Kingdom, new cases continue to appear both
sporadically and as a complication of HIV infection. There is clinica
l evidence that neurosyphilis is becoming less typical. We describe a
case of neurosyphilis presenting predominantly with choreoathetosis an
d associated hemiparesis in an otherwise healthy, immunocompetent pati
ent. Only six cases of neurosyphilis presenting with features of basal
ganglia damage have been reported in the recent literature, five of w
hom had HIV infection.