Hydranencephaly without arthrogryposis was observed in three newborn H
olstein-Friesian calves, born during one week in a 400-cow dairy herd
in Zambia. The affected calves were blind and exhibited nystagmus and
depressed behavior. Akabane virus infection was suspected based on the
pathological findings and etiological data, however, we could not det
ermine the exact causative agent.