RNA EDITING IN TRYPANOSOME MITOCHONDRIA - GUIDELINES FOR MODELS

Mitochondrial RNAs in trypanosomes are post-transcriptionally altered by uridine insertion and deletion. The information for these RNA editi ng processes, which are essential for the production of functional mes sengers, is provided by small guide RNAs. This article discusses how f eatures of partially edited RNAs, gRNAs and chimeric RNAs, in which a gRNA is covalently linked to an editing site of pre-mRNA, have been us ed for the construction of models.