Tibial nerve and S1 dermatome somatosensory evoked potentials (SSEPs)
were recorded before and after iohexol lumbar myelography in order to
evaluate possible neurotoxic effects of this contrast medium. No signi
ficant change in SSEP latencies nor amplitudes was noted after iohexol
myelography, supporting the low neurotoxic profile of this contrast a
gent. Results were compared to those of a control group of patients be
fore and after lumbar puncture (LP), without injection of contrast age
nt. In this group also no significant change in SSEP components was fo
und, indicating that a preceding LP does not affect this electrophysio
logical examination.