ACCELERATED MAXIMAL VELOCITY OF THE RED-BLOOD-CELL NA+ K+ PUMP IN HYPERLIPIDEMIA IS RELATED TO INCREASE IN 1-PALMITOYL,2-ARACHIDONOYL-PLASMALOGEN PHOSPHATIDYLETHANOLAMINE/
J. Duhm et al., ACCELERATED MAXIMAL VELOCITY OF THE RED-BLOOD-CELL NA+ K+ PUMP IN HYPERLIPIDEMIA IS RELATED TO INCREASE IN 1-PALMITOYL,2-ARACHIDONOYL-PLASMALOGEN PHOSPHATIDYLETHANOLAMINE/, Biochimica et biophysica acta, 1149(1), 1993, pp. 185-188
Among several phospholipid classes and molecular species of phosphatid
ylcholine and phosphatidylethanolamine (PE) analyzed, only the percent
age of the molecular species 1-palmitoyl,2-arachidonoyl (16:0/20:4)-pl
asmalogen-(alkenylacyl)-PE showed positive relations to the maximal ac
tivity and to the dissociation constant of the red blood cell Na+/K+ p
ump for Na+ in normo- and hyperlipidemic donors. A preferential intera
ction of this molecular species with the Na+/K+ pump is proposed.