EXTRAMAMMARY PAGETS-DISEASE

Extramammary Paget's disease (EMPD) is an epithelial disorder usually observed in cutaneous apocrine gland-bearing regions. This condition m ay be associated with either subjacent or distant malignancies or may potentially be an invasive adenocarcinoma sui generis. Clinically it i s usually recognized as a nonhealing eczematous lesion. The diagnosis is confirmed histopathologically by the presence of Paget's cells. Imm unologic studies have revealed, however, that EMPD is an entity distin ct from mammary Paget's disease.