The glucagonoma syndrome results from a tumor of the pancreatic islet
cells, specifically the alpha cells, which produce glucagon. The incid
ence of the glucagonoma syndrome is estimated to be between 1 in 20 mi
llion and 1 in 30 million per year1 with a slight female preponderance
.1 Presentation is usually between the ages of 40 and 60 (age range: 1
9-72 years).3