The activity of cysteine proteinase inhibitors was investigated in the
serum samples received from patients with head and neck tumors. Contr
ol groups involved patients with inflammatory diseases and healthy sub
jects. Active, total and complex forms of cysteine proteinase inhibito
rs were investigated. Our results revealed a striking difference betwe
en levels of determined parameters in patients with head and neck tumo
rs and in the control groups. We suggest that the determination of cys
teine proteinase inhibitors in serum may become useful in the diagnosi
s of head and neck tumors.