DETECTION OF CHLAMYDIA-TRACHOMATIS IN URINE FROM MEN WITH URETHRITIS

The performance of a commercial EIA (Chlamydiazyme) for detection of C hlamydia trachomatis in urine specimens was compared with that of cult ure of urethral samples from men with urethritis. The incidence of chl amydial infection on the basis of culture results was 34 % (56/167). T he sensitivity, specificity, positive and negative predictive values f or the EIA were 55 % (31/56), 98 % (109/111), 94 % (31/33) and 81 % (1 09/134), respectively, compared with culture. Although this EIA has a high specificity, the low sensitivity makes it valueless as a clinical tool for demonstrating chlamydial antigen in urine from men with uret hritis.