SERUM-PROTEIN MARKERS IN THE PIAROA INDIANS OF AMAZONIA (VENEZUELA)

A sample of 121 Piaroa Indians from the Federal Amazonia Territory (Ve nezuela) was studied for the following serum protein polymorphisms: ha ptoglobin (HP), group-specific component subtypes (GC), orosomucoid (O RM), third component of complement (C3), transferrin C subtypes (TF) a nd alpha1-antitrypsin subtypes (PI). The gene frequencies in the whole sample were: HP1 = 0.821; GC1S = 0.698; GC1F = 0.058; GC2 = 0.244; OR M(S) = 0.434; C3S = 0.699; C3F = 0.289; C3var = 0.012; TF(C1) = 0.955; PI(M1) = 0.467; PI(M2) = 0.004; PI(M3) = 0.529. The studied Piaroa sa mple came from three different communities: Gavilan, Paria and Alto Ca rinagua. The distribution of GC, C3 and HP polymorphisms was heterogen ous within the three groups. All the examined serum protein markers we re polymorphic, in contrast to some enzymatic markers (ADA, DIA, 6PGD, AK) previously studied, which were shown to be monomorphic in the Pia roa. The results were compared with data from other populations living in the same territory.