PHAGOCYTOSIS REDUCES HIV-1 PRODUCTION IN HUMAN MONOCYTES MACROPHAGES INFECTED IN-VITRO

Authors
PIEDIMONTE G MONTRONI M SILVESTRI G SILVOTTI L DONATINI A ROSSI L BORGHETTI AF MAGNANI M
Citation
G. Piedimonte et al., PHAGOCYTOSIS REDUCES HIV-1 PRODUCTION IN HUMAN MONOCYTES MACROPHAGES INFECTED IN-VITRO, Archives of virology, 130(3-4), 1993, pp. 463-469
Citations number
18
Categorie Soggetti
Virology
Journal title
Archives of virology → ACNP
ISSN journal
03048608
Volume
130
Issue
3-4
Year of publication
1993
Pages
463 - 469
Database
ISI
SICI code
0304-8608(1993)130:3-4<463:PRHPIH>2.0.ZU;2-W
Abstract
The addition of ingestible particles (opsonized erythrocytes or latex beads) or a phorbol ester activates monocytes - derived human macropha ges (MDHM) cultured in vitro, and markedly reduces virion release from HIV-infected MDHM as well as their ability to transmit the infection to cocultured lymphoid CD4-positive CEM cells.