STUDY OF OLIGOSACCHARIDE-BINDING RECEPTOR S OF CANCER-CELLS UNDER METASTATIC LESION OF SEROUS MEMBRANES OF THE PLEURAL CAVITY IN ONCOLOGIC PATIENTS

Authors
ABRAMENKO IV GLUZMAN DF BOVIN NV
Citation
Iv. Abramenko et al., STUDY OF OLIGOSACCHARIDE-BINDING RECEPTOR S OF CANCER-CELLS UNDER METASTATIC LESION OF SEROUS MEMBRANES OF THE PLEURAL CAVITY IN ONCOLOGIC PATIENTS, Eksperimental'naa onkologia, 15(3), 1993, pp. 40-43
Citations number
17
Categorie Soggetti
Oncology
Journal title
Eksperimental'naa onkologia → ACNP
ISSN journal
02043564
Volume
15
Issue
3
Year of publication
1993
Pages
40 - 43
Database
ISI
SICI code
0204-3564(1993)15:3<40:SOORSO>2.0.ZU;2-7
Abstract
Oligosaccharide-binding molecules of metastatic cancer cells in pleura l effusions from 26 patients have been studied using biotinylated poly acrylamide probes containing different mono- and oligosaccharides. The receptors to Thomsen-Friedenreich antigen (88,46 %), Forssman antigen (72 %), mannoso-6-phosphate (100 %), fucose (53.84 %) were revealed o n the surface and in the cytoplasm of cancer cells. The analysis of di stribution of carbohydrate-binding molecules on malignant cells has be en carried out as dependent on their phenotype and histogenesis. It gi ves ground to suppose involvement of the detected structures in the me tastatic process.