CHROMOSOMAL LOCALIZATION OF HSP70 GENES IN CATTLE

Five genomic clones representing three HSP70 genes of cattle were biot in labeled and independently hybridized to cattle chromosomes. Fluores cence in situ hybridization localized HSP70-2 to Chromosome Chr) 23 ba nd 22 (the BoLA region), HSP70-3 to Chr 10 band 34, and HSP70-4 to Chr 3 band 13. (Since HSP70-1, a fourth HSP70 gene, is tightly linked wit h HSP70-2 and the BOLA@, HSP70-1 was also localized to Chr 23 band 22. The localization of HSP704 is the first assignment of a cattle U6 mar ker; thus, this entire syntenic group is tentatively placed in cattle Chr 3.