UNUSUAL SEIZURES WITH A BENIGN COURSE IN A CASE OF ACUTE LYMPHOBLASTIC-LEUKEMIA OF CHILDHOOD

We report the unusual seizures in a patient with acute lymphoblastic l eukemia. The convulsive disorder began acutely as partial somatomotor status epilepticus and with diffuse EEG slowing. The seizures then bec ame myoclonic-atonic (drop attacks) and an EEG focus appeared on the l eft paramedian centro-parietal areas, activated by proprioceptive stim uli. Despite the severity of the clinical picture at onset, the seizur es showed a benign course, and disappeared on carbamazepine therapy. W e think that this epileptic syndrome may have been caused by diffuse i atrogenic encephalopathy, probably related to intrathecal methotrexate therapy.