DIFFERENTIATION OF KELOID AND HYPERTROPHIC SCAR - CORRELATION OF THE WATER PROTON RELAXATION-TIMES WITH THE DURATION OF THE SCAR

Citation
M. Babu et al., DIFFERENTIATION OF KELOID AND HYPERTROPHIC SCAR - CORRELATION OF THE WATER PROTON RELAXATION-TIMES WITH THE DURATION OF THE SCAR, Physiological chemistry and physics and medical NMR, 25(2), 1993, pp. 113-120
Citations number
32
Categorie Soggetti
Biophysics,Biology,Physiology,"Radiology,Nuclear Medicine & Medical Imaging
ISSN journal
07486642
Volume
25
Issue
2
Year of publication
1993
Pages
113 - 120
Database
ISI
SICI code
0748-6642(1993)25:2<113:DOKAHS>2.0.ZU;2-9
Abstract
Spin lattice relaxation times of water protons have been reported to c orrelate with the water contents of malignant as well as benign tissue s. In order to investigate whether such a correlation exists in keloid and hypertrophic scars, T1 values of keloid and hypertrophic scars we re measured using Magnetic Resonance Imaging and compared with that of normal skin. A linear correlation of the T1 values of the scars with their age was observed. Even though both the scars exhibited higher T1 values in the early stages of lesion, a faster return to the steady s tate level was observed in hypertrophic scars compared to keloids. It is suggested that the measurement of T1 values could serve to differen tiate the two abnormal wound healing situations.