SPONTANEOUS OVARIAN CHORIOCARCINOMA, YOLK-SAC CARCINOMA, AND TERATOMAIN B6C3F1 MICE - A CASE-REPORT

Authors
FRITH CH EVANS MG
Citation
Ch. Frith et Mg. Evans, SPONTANEOUS OVARIAN CHORIOCARCINOMA, YOLK-SAC CARCINOMA, AND TERATOMAIN B6C3F1 MICE - A CASE-REPORT, Toxicologic pathology, 21(1), 1993, pp. 91-98
Citations number
NO
Categorie Soggetti
Toxicology,Pathology
Journal title
Toxicologic pathology → ACNP
ISSN journal
01926233
Volume
21
Issue
1
Year of publication
1993
Pages
91 - 98
Database
ISI
SICI code
0192-6233(1993)21:1<91:SOCYCA>2.0.ZU;2-8
Abstract
Three ovarian neoplasms (choriocarcinoma, yolk sac carcinoma, and tera toma) were diagnosed in a 2 yr carcinogenicity study involving B6C3F1 mice. The yolk sac carcinoma and the teratoma occurred in opposite ova ries of a single female mouse that was sacrificed in extremis on study day 725. The choriocarcinoma occurred in a female mouse that was sacr ificed in extremis on study day 565. These neoplasms were considered t o be spontaneous in origin.