Depending on the severity of the injury, high endotoxin levels may be
found in patients with lung contusion but only slightly increased leve
ls in patients with skull and brain trauma. This difference is highly
significant. Patients with multiple injuries and fractures of the extr
emities as the main diagnosis and with a combination of injuries show
a moderate increase in endoxin level on the day of admission. There is
no relationship between the injury severity and endotoxemia.