An audit of the treatment of patients (100 men and 90 women) presentin
g with a first episode of anogenital warts to the Genitourinary Medici
ne Department at Leeds General Infirmary was performed. Treatment of p
atients was monitored for a period of 6 months from the time of presen
tation. The management of patients with genital warts lacked a clearly
defined strategy and treatment was unselective and poorly monitored.
Excluding patients who defaulted, at follow-up 44 (44%) men and 36 (38
%) women still had genital warts at 3 months. Of those patients clear
of warts at 3 months, the mean time to remission for men and women was
7.1 and 8.3 weeks respectively. Podophylin 25% in tincture of benzoin
was by far the predominant therapeutic modality used. A total of 96 (
96%) men and 76 (84%) women received treatment with podophyllin. Both
male and female patients had a mean of 5 treatments with podophyllin 2
5% (range 1-19 and 1-12 respectively). Physical methods of treatment i
.e. cryotherapy and electrocautery, were underutilized, both as primar
y therapies and when topical agents had failed. Patients saw an averag
e of 3 (range 1-7) doctors over the course of their treatment. Patient
s with warts affecting 2 or more sites, male patients with anal/perian
al warts, and female patients with cervical and vaginal warts had high
er failure rates from treatment at 3 months. On the basis of these fin
dings, specific treatment protocols for the management of anogenital w
arts have been devised.