Background: Persistent epithelial defects of the cornea are difficult
to treat and can lead to severe complications such as melting processe
s. Therefore the application of a glued-on hard contact lens as an art
ificial epithelium has been recommended for many years, to protect the
denuded corneal stroma. Materials and methods: This paper presents a
7-year retrospective study on the application of a hard contact lens a
s an artificial epithelium. 46 patients with 50 eyes were treated with
this method from january 1985 to march 1992. The majority of the pati
ents suffered from most severe bums of the whole anterior eye segment
(group I: n = 29 eyes) or of the cornea alone (group II: n = 13 eyes).
A smaller number of patients (group III: n = 8 eyes) presented cornea
l melting processes associated with other diseases. Results: The patie
nts of group II and III showed the best outcome concerning spontaneous
epithelization and prognosis for a penetrating keratoplasty. The trea
tment with a glued-on hard contact lens was limited by the high rate o
f complications (92%) in group I and II. In one third of the cases of
group I these complications led to further surgical interventions (e.g
. conjunctivoplasty of the globe). The results also show, that the app
lication of a glued-on hard contact lens in patients with most severe
eye bums is a long-term treatment (> one year). Conclusion: The poor p
rognosis of corneas with severe healing problems of the epithelium can
be improved by the application of a glued-on hard contact lens as an
artificial epithelium. In severe burns of the whole anterior eye segme
nt however, the treatment with an early keratoplasty should be conside
red.