G. Mielke et al., PRENATAL-DIAGNOSIS OF IDIOPATHIC STENOSIS OF THE DUCTUS-ARTERIOSUS ASSOCIATED WITH FETAL ATRIAL-FLUTTER, Fetal diagnosis and therapy, 12(1), 1997, pp. 46-49
Antenatal stenosis or closure of the ductus arteriosus unrelated to ei
ther congenital heart defects or prostaglandin inhibitors is considere
d to be uncommon, but may result in congestive heart failure, hydrops
fetalis, and perinatal death. We report a case of idiopathic ductal st
enosis detected prenatally by two-dimensional and Doppler echocardiogr
aphy in a fetus presenting atrial flutter and right atrial dilatation
at 31 weeks of gestation. Prenatal treatment with digoxin and verapami
l resulted in conversion to sinus rhythm, The fetus was closely monito
red, Congestive heart failure did not develop, and the fetus was deliv
ered spontaneously in good condition at 39 weeks of gestation. In case
of ductal stenosis, the potential risk of congestive heart failure mu
st be considered, and maternal administration of drugs with constricti
ve effects on the ductus arteriosus, as indomethacin or betamethasone,
should be avoided.