Recent findings have led to important changes in the understanding of
HIV kinetics that allowed a novel therapeutic approach. This article r
eviews the most common methods used to gauge viral load and their use
in medical decision making, the characteristics of the protease inhibi
tors just released in Argentina, and preliminary reports from several
trials of combined treatment that have changed the standard of care. T
he viral load is a surrogate marker with predictive value independent
of the CD4 cell count. Combined treatment is the election in case it i
s decided to initiate treatment.