T. Gopaldas et al., PREVALENCE OF XEROPHTHALMIA AND EFFICACY OF VITAMIN-A PROPHYLAXIS IN PREVENTING XEROPHTHALMIA COEXISTING WITH MALNUTRITION IN RURAL INDIAN CHILDREN, Journal of tropical pediatrics, 39(4), 1993, pp. 205-208
Data of 4302 children, 0-6 years old were analysed to study the preval
ence of vitamin A deficiency and the efficacy of vitamin A prophylaxis
in preventing xerophthalmia co-existing with malnutrition. Manifestat
ion of ocular signs of vitamin A deficiency were seen in 10 per cent c
hildren. The prevalence of xerophthalmia was higher in the normal and
mild to moderately malnourished children, and lowest in the severely m
alnourished ones. The ability of vitamin A prophylaxis to curb xeropht
halmia was greatest at the extreme ends of the nutritional grade spect
rum. These findings have important implications for the existing natio
nal Vitamin A Prophylaxis Programme, and suggest that: (a) normal and
mild to moderately malnourished children less than 6 years old, should
be preferably considered for vitamin A mega dosing; (b) in the manage
ment of protein energy malnutrition, vitamin A status of the children
should be monitored; and (c) the coverage should be improved as most c
hildren are in the mild and moderate degrees of malnutrition.