In a prospective study of 302 ureteroscopic procedures, 161 were comme
nced and 133 completed without the use of general or regional anaesthe
sia. In 15 patients ureteroscopy (URS) was performed with lignocaine j
elly in the urethra only, and in 1 18 with additional intravenous anal
gesia. Alfentanil, a synthetic morphine derivative, was used for intra
venous analgesia. Ureteroscopy was performed prior to extracorporeal s
hock wave lithotripsy in 46 patients, for stone basketing in 40, for s
tone fragmentation in 29, for diagnostic purposes in 14 and for cold k
nife ureterotomy in 4. Ureteric lesions were observed in 9 patients (6
.8%) treated under intravenous sedoanalgesia. This percentage is withi
n the range reported in other series of patients treated under general
anaesthesia. The findings suggest that URS, when performed without ge
neral or regional anaesthesia, does not increase the risk of complicat
ions or compromise the results of treatment.