SPONTANEOUS CLOSURE OF INLET VENTRICULAR SEPTAL-DEFECT IN AN INFANT WITH DOWNS-SYNDROME AND AORTIC COARCTATION

Ventricular septal defect (VSD) is considered one of the most common c ongenital heart diseases in patients with Down's syndrome. It is well known that some VSDs show a tendency to diminish in size and to close. To our knowledge, in patients with Down's syndrome spontaneous closur e of a perimembranous inlet VSD has not been described before. The pre valence of some cardiac malformations and the rarity of others have be en reported in patients with Down's syndrome. Left ventricular outflow tract obstruction rarely occurs in patients with Down's syndrome. A c ase of Down's syndrome with coarctation of the aorta, patent ductus ar teriosus, and perimembranous inlet VSD that spontaneously closed by fo rmation of aneurysm of the membranous septum is reported.