THE MAJOR CAPSID PROTEIN VP2 OF MINUTE VIRUS OF MICE (MVM) CAN FORM PARTICLES WHICH BIND TO THE 3'-TERMINAL HAIRPIN OF MVM REPLICATIVE-FORMDNA AND PACKAGE SINGLE-STRANDED VIRAL PROGENY DNA
K. Willwand et B. Hirt, THE MAJOR CAPSID PROTEIN VP2 OF MINUTE VIRUS OF MICE (MVM) CAN FORM PARTICLES WHICH BIND TO THE 3'-TERMINAL HAIRPIN OF MVM REPLICATIVE-FORMDNA AND PACKAGE SINGLE-STRANDED VIRAL PROGENY DNA, Journal of virology, 67(9), 1993, pp. 5660-5663
The capsids of minute virus of mice (MVM) consist of two closely relat
ed proteins, VP1 and VP2. We inactivated the VP1 gene in an infectious
clone of MVM DNA by frameshift mutation. After transfection of mutate
d DNA, capsids consisting of VP2 only were made. They can package nega
tive-strand DNA, and they specifically bind MVM 3'-terminal hairpin DN
A.