THE MAJOR CAPSID PROTEIN VP2 OF MINUTE VIRUS OF MICE (MVM) CAN FORM PARTICLES WHICH BIND TO THE 3'-TERMINAL HAIRPIN OF MVM REPLICATIVE-FORMDNA AND PACKAGE SINGLE-STRANDED VIRAL PROGENY DNA

Authors
WILLWAND K HIRT B
Citation
K. Willwand et B. Hirt, THE MAJOR CAPSID PROTEIN VP2 OF MINUTE VIRUS OF MICE (MVM) CAN FORM PARTICLES WHICH BIND TO THE 3'-TERMINAL HAIRPIN OF MVM REPLICATIVE-FORMDNA AND PACKAGE SINGLE-STRANDED VIRAL PROGENY DNA, Journal of virology, 67(9), 1993, pp. 5660-5663
Citations number
19
Categorie Soggetti
Virology
Journal title
Journal of virology → ACNP
ISSN journal
0022538X
Volume
67
Issue
9
Year of publication
1993
Pages
5660 - 5663
Database
ISI
SICI code
0022-538X(1993)67:9<5660:TMCPVO>2.0.ZU;2-W
Abstract
The capsids of minute virus of mice (MVM) consist of two closely relat ed proteins, VP1 and VP2. We inactivated the VP1 gene in an infectious clone of MVM DNA by frameshift mutation. After transfection of mutate d DNA, capsids consisting of VP2 only were made. They can package nega tive-strand DNA, and they specifically bind MVM 3'-terminal hairpin DN A.