INTRACAVERNOUS SODIUM-NITROPRUSSIDE - INAPPROPRIATE IMPOTENCE TREATMENT

Authors
BROCK G BREZA J LUE TF
Citation
G. Brock et al., INTRACAVERNOUS SODIUM-NITROPRUSSIDE - INAPPROPRIATE IMPOTENCE TREATMENT, The Journal of urology, 150(3), 1993, pp. 864-867
Citations number
22
Categorie Soggetti
Urology & Nephrology
Journal title
The Journal of urology → ACNP
ISSN journal
00225347
Volume
150
Issue
3
Year of publication
1993
Pages
864 - 867
Database
ISI
SICI code
0022-5347(1993)150:3<864:IS-IIT>2.0.ZU;2-2
Abstract
On the basis of reports describing nitric oxide as a form of endotheli um-derived relaxing factor and on our own experience with intracaverno us use of nitric oxide-releasing substances in animal models, we under took an approved human study of intracavernous sodium nitroprusside as a treatment for impotence. We report our early experience in which se vere hypotension and only mild tumescence in our first 3 patients caus ed us to discontinue the trial.