CYTOGENETIC CHANGES IN 67 CRANIAL AND SPINAL MENINGIOMAS - RELATION TO HISTOPATHOLOGICAL AND CLINICAL-PATTERN

Authors
DOCOFENZY M CORNILLET P SCHERPEREEL B DEPERNET B BISIAULECONTE S FERRE D PLUOT M GRAFTIAUX JP TEYSSIER JR
Citation
M. Docofenzy et al., CYTOGENETIC CHANGES IN 67 CRANIAL AND SPINAL MENINGIOMAS - RELATION TO HISTOPATHOLOGICAL AND CLINICAL-PATTERN, Anticancer research, 13(4), 1993, pp. 845-850
Citations number
28
Categorie Soggetti
Oncology
Journal title
Anticancer research → ACNP
ISSN journal
02507005
Volume
13
Issue
4
Year of publication
1993
Pages
845 - 850
Database
ISI
SICI code
0250-7005(1993)13:4<845:CCI6CA>2.0.ZU;2-6
Abstract
The cytogenetic analysis of 67 meningiomas (58 intracranial and 9 spin al tumors) identified chromosomal abnormalities in 63% of cases. When chromosomes involved in numerical and structural changes with a freque ncy of more than one standard deviation above the mean were considered , distinct cytogenetic patterns could be identified according to sex, anatomical location and histology. The chromosomes more frequently aff ected were 1, 2, 3, 4, 8, 14, 15, 19, 22, Y. No conclusion could be dr awn regarding the prognostic significance of these karyotypic alterati ons.